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B3.3 Muscle and motility

Tags
myofibril
sarcomere
actin
myosin
sliding filament
troponin
tropomyosin
power stroke
ventilation
neuromuscular junction
intercostal muscle
synovial joint
hinge joint

Understanding points

B3.3.1 Adaptations for movement as a universal feature of living organisms (HL only) B3.3.2 Sliding filament model of muscle contraction (HL only) B3.3.3 Role of the protein titin and antagonistic muscles in muscle relaxation (HL only) B3.3.4 Structure and function of motor units in skeletal muscle (HL only) B3.3.5 Roles of skeletons as anchorage for muscles and as levers (HL only) B3.3.6 Movement at a synovial joint (HL only) B3.3.7 Range of motion of a joint (HL only) B3.3.8 Internal and external intercostal muscles as an example of antagonistic muscle action to facilitate internal body movements (HL only) B3.3.9 Reasons for locomotion (HL only) B3.3.10 Adaptations for swimming in marine mammals (HL only)

Muscle structure

Muscle fibre structure

Multinucleate
Muscle fibres are individual muscle cells fused together → many nuclei
Many mitochondria
Muscle contraction requires ATP hydrolysis
Sarcoplasmic reticulum
Specialized endoplasmic reticulum that stores Ca²⁺ ions
Tubular myofibrils
Made up of thin actin filament and thick myosin filament
Sarcolemma
Continuous membrane surrounding the muscle fibre that contains invaginations called T tubules

Sarcomere

Repeating contractile units composed of two myofilaments: actin and myosin
The thick filament (myosin) contains small protruding heads which bind to the thin filament (actin)
Movement of these filaments relative to one another causes lengthening /shortening of sarcomere

Sliding filament model of muscle contraction

Nerve impulse depolarizes sarcolemma ↓ Ca²⁺ released from sarcoplasmic reticulum ↓ Ca²⁺ bind to troponin, causing tropomyosin to expose binding sites on actin ↓ Myosin heads form cross-bridge with actin ↓ Myosin heads cause a power stroke by pulling ↓ Z-line moves closer ↓ ATP binding breaks cross-bridge = moves back to original place

Muscle relaxation: by titin

Stores potential energy during muscle relaxation, releases it during contraction
Connects myosin filaments to the Z disc and keeps them in the center
Prevents overstretching of the sarcomere

Motor units

Neuromuscular junction: the synapse between a motor neuron and a muscle fiber
Motor unit = motor neuron + all the muscle fibers it stimulates
Allows coordinated contraction of muscles

Intercostal muscles

The antagonistic action of internal and external intercostal muscles enables ventilation of the lungs
Internal muscles contract: ribcage moves in and down → lung volume decreases → exhalation
External muscles contract: ribcage moves up and out → lung volume increases → inhalation

Synovial joints

Capsules that surround the articulating surfaces of two bones
Provide structural stability by allowing certain movements
Composition:
1.
Joint capsule : seals joint space and provides stability by restricting the range of movement
2.
Cartilage: lines the bone surface to facilitate smoother movement, absorbs shock, distributes load
3.
Synovial fluid: provides oxygen and nutrition to the cartilage, as well as lubrication

Human elbow

A hinge joint that is located between the humerus and radius / ulna
Capable of angular movement in one direction
Biceps : bends forearm (flexion)
Triceps : straightens forearm (extension)