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B3.1 Gas exchange

Tags
ventilation
gas exchange
spirometer
emphysema
mesophyll
transpiration
stomata
hemoglobin
Bohr shift
cooperative binding

Understanding points

B3.1.1 Gas exchange as a vital function in all organisms B3.1.2 Properties of gas-exchange surfaces B3.1.3 Maintenance of concentration gradients at exchange surfaces in animals B3.1.4 Adaptations of mammalian lungs for gas exchange B3.1.5 Ventilation of the lungs B3.1.6 Measurement of lung volumes B3.1.7 Adaptations for gas exchange in leaves B3.1.8 Distribution of tissues in a leaf B3.1.9 Transpiration as a consequence of gas exchange in a leaf B3.1.10 Stomatal density B3.1.11 Adaptations of foetal and adult haemoglobin for the transport of oxygen (HL only) B3.1.12 Bohr shift (HL only) B3.1.13 Oxygen dissociation curves as a means of representing the affinity of haemoglobin for oxygen at different oxygen concentrations (HL only)

Ventilation, cell respiration, gas exchange

Ventilation
Exchange of air between the atmosphere and the lungs
Achieved by the physical act of breathing
Cell respiration
Generation of ATP from organic molecules
Enhanced by the presence of oxygen
Gas exchange
Exchange of O₂ and CO₂ between the alveoli and bloodstream by passive diffusion
Gas exchange surfaces must be thin, moist, permeable, and have a large SA
Ventilation and dense capillary networks maintain conc gradients for diffusion

Adaptations of the lung

Airways
Bronchi - bronchioles - alveoli
Large SA
300 million alveoli in a pair of adult lungs
Extensive capillary beds
Surround the alveoli like a basket
Short diffusion distances
Capillary and alveoli walls are a single cell thick
Pulmonary surfactant
Reduces surface tension and prevents alveolar collapse

Lung ventilation

Exchanges gases between inhaled air and lungs
Maintains high con. gradient of gases in alveoli of the lungs
Aided by diaphragm and intercostal muscles
Inspiration
Expiration
External intercostal muscles contract & internal intercostal muscles relax  ↓ Rib cage is pulled upwards & diaphragm contracts and flattens  ↓ Thoracic cavity volume increases ↓ Decrease in pressure causes air to enter the lungs
Internal intercostal muscles contract & external intercostal muscles relax  ↓ Rib cage moves downwards  & diaphragm relaxes and moves upwards ↓ Thoracic cavity volume decreases ↓ Increase in the pressure causes air to exit the lungs

Spirometer

Used to measure lung volumes
Lung volumes are used to diagnose asthma, COPD, cystic fibrosis
A simpler method uses a balloon to measure the volume of air in a single breath: submerging the balloon in water and measuring the volume displaced (1mL = 1cm³)
Alveolar ventilation rate = # of breath x (tidal volume – dead space)
Actual v. of gas involved in ventilation
To increase alveolar ventilation
1.
Increase ventilation rate by increasing greater frequency of breaths
2.
Increase tidal volume increasing the volume of air taken in and out per breath

Emphysema

Cause: chemical irritants in cigarette smoke damage the alveolar walls and reduce their elasticity
Rich blood supply increases the likelihood of the cancer metastasis
Uncontrolled proliferation of lung cells leads to the abnormal growth of lung tissue

Adaptations for gas exchange in leaves

Waxy cuticle
Covers the upper and lower layers of leaves Reduces water loss and prevents movement of O₂ and CO₂
Guard cells
Close the stomata at night when photosynthesis is not occurring and gas exchange is not required
Spongy mesophyll
Contains extensive air spaces and provides a large SA

Transpiration

Loss of water vapor from the leaves and stems of plants
Increases at higher temperature because evaporation rate is higher
Increases in the presence of wind because it dissipates saturated air near stomata
Decreases when humidity is high because the conc gradient is smaller
Light intensity is an essential factor for transpiration

Stomatal density

Number of stomata per unit area
Higher stomatal density can increase both carbon dioxide uptake and water loss.
Stomatal density differs between different species of plants because they are adapted to the environment they live in.

*(AHL)

Adaptations of fetal and adult hemoglobin for oxygen transport

Fetal hemoglobin has a higher affinity for oxygen than adult hemoglobin
At any pO₂, fetal hemoglobin is more saturated than adult hemoglobin
This allows the fetus to obtain oxygen from the placenta

Bohr shift

High CO₂ concentrations reduce the affinity of hemoglobin for oxygen
1.
CO₂ decreases pH: hemoglobin has lower affinity at lower pH
2.
CO₂ binds to hemoglobin: carbaminohemoglobin has a lower affinity than hemoglobin
The result is a shift in the oxygen dissociation curve to the left
Promotes release of oxygen in actively respiring tissues with high CO₂ conc
Promotes oxygenation of blood in the lungs with low CO₂ conc

Oxygen dissociation curves

Cooperative binding of oxygen to a heme group induces a conformational change that increases the affinity for oxygen in other heme groups
Thus, the oxygen saturation of hemoglobin is not directly proportional to pO₂
Instead, it changes from fully unsaturated to fully saturated over a narrow range of pO₂
This enables rapid dissociation of O₂ in respiring tissues